Cargando…

MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor

High plasma LDL cholesterol (LDL-c) concentration is a major risk factor for atherosclerosis. Hepatic LDL receptor (LDLR) regulates LDL metabolism, and thereby plasma LDL-c concentration. Recently, we have identified the (pro)renin receptor [(P)RR] as a novel regulator of LDL metabolism, which regul...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Na, He, Lishu, Lin, Hui, Tan, Lunbo, Sun, Yuan, Zhang, Xiaoying, Danser, A. H. Jan, Lu, Hong S., He, Yongcheng, Lu, Xifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241754/
https://www.ncbi.nlm.nih.gov/pubmed/32437440
http://dx.doi.org/10.1371/journal.pone.0225356