Cargando…

MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor

High plasma LDL cholesterol (LDL-c) concentration is a major risk factor for atherosclerosis. Hepatic LDL receptor (LDLR) regulates LDL metabolism, and thereby plasma LDL-c concentration. Recently, we have identified the (pro)renin receptor [(P)RR] as a novel regulator of LDL metabolism, which regul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Na, He, Lishu, Lin, Hui, Tan, Lunbo, Sun, Yuan, Zhang, Xiaoying, Danser, A. H. Jan, Lu, Hong S., He, Yongcheng, Lu, Xifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241754/ https://www.ncbi.nlm.nih.gov/pubmed/32437440 http://dx.doi.org/10.1371/journal.pone.0225356

Ejemplares similares

Megalin, Proton Pump Inhibitors and the Renin–Angiotensin System in Healthy and Pre-Eclamptic Placentas
por: Sun, Yuan, et al.
Publicado: (2021)

(Pro)renin Receptor Inhibition Reduces Plasma Cholesterol and Triglycerides but Does Not Attenuate Atherosclerosis in Atherosclerotic Mice
por: Ye, Dien, et al.
Publicado: (2021)

The (pro)renin receptor. A decade of research: what have we learned?
por: Krop, Manne, et al.
Publicado: (2012)

The Role of Chemerin in Metabolic and Cardiovascular Disease: A Literature Review of Its Physiology and Pathology from a Nutritional Perspective
por: Tan, Lunbo, et al.
Publicado: (2023)

Revisiting the Brain Renin-Angiotensin System—Focus on Novel Therapies
por: Ren, Liwei, et al.
Publicado: (2019)

Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?
por: Sun, Yuan, et al.
Publicado: (2020)

MicroRNA-148a Regulates the Proliferation and Differentiation of Ovine Preadipocytes by Targeting PTEN
por: Jin, Xiayang, et al.
Publicado: (2021)

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo
por: Maschmeyer, Patrick, et al.
Publicado: (2018)

MicroRNA-152 represses VEGF and TGFβ1 expressions through post-transcriptional inhibition of (Pro)renin receptor in human retinal endothelial cells
por: Haque, Rashidul, et al.
Publicado: (2015)

The MicroRNA-148/152 Family: Multi-faceted Players
por: Chen, Yue, et al.
Publicado: (2013)

MicroRNA-21 and microRNA-148a affects PTEN, NO and ROS in canine leishmaniasis
por: De Freitas, Jéssica Henrique, et al.
Publicado: (2023)

GEN-09 Pursuing the function of microRNA targeting (Pro)renin receptor against glioma
por: Ogawa, Daisuke, et al.
Publicado: (2020)

MicroRNA-146 represses endothelial activation by inhibiting pro-inflammatory pathways
por: Cheng, Henry S, et al.
Publicado: (2013)

MicroRNA-148a-3p inhibits progression of hepatocelluar carcimoma by repressing SMAD2 expression in an Ago2 dependent manner
por: Huang, Zhao, et al.
Publicado: (2020)

Correlations between serum levels of microRNA-148a-3p and microRNA-485-5p and the progression and recurrence of prostate cancer
por: He, Wenyan, et al.
Publicado: (2022)

Combined Renin Inhibition/(Pro)Renin Receptor Blockade in Diabetic Retinopathy- A Study in Transgenic (mREN2)27 Rats
por: Batenburg, Wendy W., et al.
Publicado: (2014)

MicroRNAs are Transported in Plasma and Delivered to Recipient Cells by High-Density Lipoproteins
por: Vickers, Kasey C., et al.
Publicado: (2011)

Activation of (pro)renin by (pro)renin receptor in extracellular vesicles from osteoclasts
por: Murray, Jonathan B., et al.
Publicado: (2021)

Increased expression of microRNA-148a in osteosarcoma promotes cancer cell growth by targeting PTEN
por: Zhang, Hao, et al.
Publicado: (2016)

Overexpression of MicroRNA-148b-3p stimulates osteogenesis of human bone marrow-derived mesenchymal stem cells: the role of MicroRNA-148b-3p in osteogenesis
por: Mollazadeh, Samaneh, et al.
Publicado: (2019)

MicroRNA‐590‐3p inhibits trophoblast‐dependent maternal spiral artery remodeling by repressing low‐density lipoprotein receptor‐related protein 6
por: Zhang, Yinghong, et al.
Publicado: (2018)

MicroRNA-148a inhibits breast cancer migration and invasion by directly targeting WNT-1
por: Jiang, Qian, et al.
Publicado: (2022)

Colocalization of the (Pro)renin Receptor/Atp6ap2 with H(+)-ATPases in Mouse Kidney but Prorenin Does Not Acutely Regulate Intercalated Cell H(+)-ATPase Activity
por: Daryadel, Arezoo, et al.
Publicado: (2016)

Regulation of the (pro)renin–renin receptor in cardiac remodelling
por: Mahmud, Hasan, et al.
Publicado: (2012)

Nuclear Localization of Argonaute is affected by Cell Density and May Relieve Repression by microRNAs
por: Johnson, Krystal C., et al.
Publicado: (2023)

The Predictive Efficacy of Serum Exosomal microRNA-122 and microRNA-148a for Hepatocellular Carcinoma Based on Smart Healthcare
por: Deng, Peng, et al.
Publicado: (2022)

Clinical significance of promoter region hypermethylation of microRNA-148a in gastrointestinal cancers
por: Sun, Jingxu, et al.
Publicado: (2014)

MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice
por: Cheng, Li, et al.
Publicado: (2017)

MicroRNAs 145 and 148a Are Upregulated During Congenital Zika Virus Infection
por: Castro, Fernanda L., et al.
Publicado: (2019)

The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity
por: Gonzalez-Martin, Alicia, et al.
Publicado: (2016)

Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers
por: Danser, A.H. Jan, et al.
Publicado: (2020)

Autophagy and the (Pro)renin Receptor
por: Binger, Katrina J., et al.
Publicado: (2013)

MicroRNA-148a suppresses proliferation and invasion potential of non-small cell lung carcinomas via regulation of STAT3
por: He, Mei, et al.
Publicado: (2017)

Modulation of the Cellular microRNA Landscape: Contribution to the Protective Effects of High-Density Lipoproteins (HDL)
por: Graham, Annette
Publicado: (2023)

MicroRNA 148a Suppresses Tuberculous Fibrosis by Targeting NOX4 and POLDIP2
por: Woo, Seong Ji, et al.
Publicado: (2022)

3’UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells
por: Hoffman, Yonit, et al.
Publicado: (2016)

Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism
por: Watanabe, Daisuke, et al.
Publicado: (2020)

Fine-tuning of microRNA-mediated repression of mRNA by splicing-regulated and highly repressive microRNA recognition element
por: Wu, Cheng-Tao, et al.
Publicado: (2013)

Downregulated microRNA-133a induces HUVECs injury: Potential role of the (pro) renin receptor in angiotensin II-dependent hypertension
por: Liu, Bing, et al.
Publicado: (2019)

The Impact of microRNAs in Renin–Angiotensin-System-Induced Cardiac Remodelling
por: Adamcova, Michaela, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cpuaj4fmhm8el8njve4isgf00m