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THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation

Lipoprotein lipase (LPL) is upregulated in atherosclerotic lesions and it may promote the progression of atherosclerosis, but the mechanisms behind this process are not completely understood. We previously showed that the phosphorylation of Akt within THP-1 macrophages is increased in response to th...

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Detalles Bibliográficos
Autores principales: Marshall, Jenika D., Courage, Emily R., Elliott, Ryan F., Fitzpatrick, Madeline N., Kim, Anne D., Lopez-Clavijo, Andrea F., Woolfrey, Bronwyn A., Ouimet, Mireille, Wakelam, Michael J. O., Brown, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241781/
https://www.ncbi.nlm.nih.gov/pubmed/32437392
http://dx.doi.org/10.1371/journal.pone.0233180