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ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing

Allele-specific expression (ASE) analysis, which quantifies the relative expression of two alleles in a diploid individual, is a powerful tool for identifying cis-regulated gene expression variations that underlie phenotypic differences among individuals. Existing methods for gene-level ASE detectio...

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Detalles Bibliográficos
Autores principales: Fan, Jiaxin, Hu, Jian, Xue, Chenyi, Zhang, Hanrui, Susztak, Katalin, Reilly, Muredach P., Xiao, Rui, Li, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241832/
https://www.ncbi.nlm.nih.gov/pubmed/32392242
http://dx.doi.org/10.1371/journal.pgen.1008786