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ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing
Allele-specific expression (ASE) analysis, which quantifies the relative expression of two alleles in a diploid individual, is a powerful tool for identifying cis-regulated gene expression variations that underlie phenotypic differences among individuals. Existing methods for gene-level ASE detectio...
Autores principales: | Fan, Jiaxin, Hu, Jian, Xue, Chenyi, Zhang, Hanrui, Susztak, Katalin, Reilly, Muredach P., Xiao, Rui, Li, Mingyao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241832/ https://www.ncbi.nlm.nih.gov/pubmed/32392242 http://dx.doi.org/10.1371/journal.pgen.1008786 |
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