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Disrupted glycosylation of lipids and proteins is a cause of neurodegeneration

Glycosyltransferases represent a large family of enzymes that catalyse the biosynthesis of oligosaccharides, polysaccharides, and glycoconjugates. A number of studies have implicated glycosyltransferases in the pathogenesis of neurodegenerative diseases but differentiating cause from effect has been...

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Detalles Bibliográficos
Autores principales: Moll, Tobias, Shaw, Pamela J, Cooper-Knock, Johnathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241952/
https://www.ncbi.nlm.nih.gov/pubmed/31724708
http://dx.doi.org/10.1093/brain/awz358