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Deficient Resident Memory T Cell and CD8 T Cell Response to Commensals in Inflammatory Bowel Disease

BACKGROUND AND AIMS: The intestinal microbiota is closely associated with resident memory lymphocytes in mucosal tissue. We sought to understand how acquired cellular and humoral immunity to the microbiota differ in health versus inflammatory bowel disease [IBD]. METHODS: Resident memory T cells [Tr...

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Detalles Bibliográficos
Autores principales: Noble, Alistair, Durant, Lydia, Hoyles, Lesley, Mccartney, Anne L, Man, Ripple, Segal, Jonathan, Costello, Samuel P, Hendy, Philip, Reddi, Durga, Bouri, Sonia, Lim, Dennis N F, Pring, Toby, O’Connor, Matthew J, Datt, Pooja, Wilson, Ana, Arebi, Naila, Akbar, Ayesha, Hart, Ailsa L, Carding, Simon R, Knight, Stella C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242004/
https://www.ncbi.nlm.nih.gov/pubmed/31665283
http://dx.doi.org/10.1093/ecco-jcc/jjz175