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Cryo-EM structures and functional properties of CALHM channels of the human placenta

The transport of substances across the placenta is essential for the development of the fetus. Here, we were interested in the role of channels of the calcium homeostasis modulator (CALHM) family in the human placenta. By transcript analysis, we found the paralogs CALHM2, 4, and 6 to be highly expre...

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Detalles Bibliográficos
Autores principales: Drożdżyk, Katarzyna, Sawicka, Marta, Bahamonde-Santos, Maria-Isabel, Jonas, Zaugg, Deneka, Dawid, Albrecht, Christiane, Dutzler, Raimund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242029/
https://www.ncbi.nlm.nih.gov/pubmed/32374262
http://dx.doi.org/10.7554/eLife.55853