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Differential Diabetogenic Effect of Pitavastatin and Rosuvastatin, in vitro and in vivo

Aim: Most statins increase the risk of new-onset diabetes. Unlike other statins, pitavastatin is reported to exert neutral effects on serum glucose level, but the precise mechanism is unknown. Methods: Eight-week-old male C57BL/6J mice (n = 26) were fed high-fat diet (HFD, 45% fat) with 0.01% placeb...

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Detalles Bibliográficos
Autores principales: Cho, Yongin, Lee, Hyangkyu, Park, Hyun Ki, Choe, Eun Yeong, Wang, Hye Jin, Kim, Ryeong-Hyeon, Kim, Youjin, Kang, Eun Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242225/
https://www.ncbi.nlm.nih.gov/pubmed/31527323
http://dx.doi.org/10.5551/jat.50039