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Quantification of Radiation Injury on Neutropenia and the Link between Absolute Neutrophil Count Time Course and Overall Survival in Nonhuman Primates Treated with G-CSF

PURPOSE: To model absolute neutrophil count (ANC) suppression in response to acute radiation (AR) exposure and evaluate ANC time course as a predictor of overall survival (OS) in response to AR exposure with or without treatment with granulocyte colony-stimulating factor in nonhuman primates. METHOD...

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Detalles Bibliográficos
Autores principales: Harrold, John, Gisleskog, Per Olsson, Delor, Isabelle, Jacqmin, Philippe, Perez-Ruixo, Juan Jose, Narayanan, Adimoolam, Doshi, Sameer, Chow, Andrew, Yang, Bing-Bing, Melhem, Murad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242243/
https://www.ncbi.nlm.nih.gov/pubmed/32440783
http://dx.doi.org/10.1007/s11095-020-02839-3