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Metabolic features of cancer cells in NRF2 addiction status

The KEAP1-NRF2 system is a sulfur-employing defense mechanism against oxidative and electrophilic stress. NRF2 is a potent transcription activator for genes mediating sulfur-involving redox reactions, and KEAP1 controls the NRF2 activity in response to the stimuli by utilizing reactivity of sulfur a...

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Detalles Bibliográficos
Autores principales: Okazaki, Keito, Papagiannakopoulos, Thales, Motohashi, Hozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242251/
https://www.ncbi.nlm.nih.gov/pubmed/32112372
http://dx.doi.org/10.1007/s12551-020-00659-8