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Impact of Magnesium Stearate Presence and Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties

Excipients are major components of oral solid dosage forms, and changes in their critical material attributes (excipient variability) and/or amount (excipient variation) in pharmaceutical formulations may present a challenge for product performance. Understanding the biopharmaceutical factors affect...

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Detalles Bibliográficos
Autores principales: Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Fotaki, Nikoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242257/
https://www.ncbi.nlm.nih.gov/pubmed/32440810
http://dx.doi.org/10.1208/s12248-020-00449-w