Cargando…
Impact of Magnesium Stearate Presence and Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties
Excipients are major components of oral solid dosage forms, and changes in their critical material attributes (excipient variability) and/or amount (excipient variation) in pharmaceutical formulations may present a challenge for product performance. Understanding the biopharmaceutical factors affect...
Autores principales: | Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Fotaki, Nikoletta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242257/ https://www.ncbi.nlm.nih.gov/pubmed/32440810 http://dx.doi.org/10.1208/s12248-020-00449-w |
Ejemplares similares
-
Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties. Case Study: Superdisintegrants
por: Zarmpi, Panagiota, et al.
Publicado: (2020) -
Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties: Case Study—Hypromellose (HPMC)
por: Zarmpi, P., et al.
Publicado: (2020) -
Co-administration of Paediatric Medicines with Food and Drinks in the Context of Their Physicochemical Properties—a Global Perspective on Practices and Recommendations
por: Martir, Joana, et al.
Publicado: (2020) -
Impact of Food and Drink Administration Vehicles on
Paediatric Formulation Performance: Part 1—Effects on Solubility of Poorly Soluble
Drugs
por: Martir, J., et al.
Publicado: (2020) -
Impact of Leucine and Magnesium Stearate on the Physicochemical Properties and Aerosolization Behavior of Wet Milled Inhalable Ibuprofen Microparticles for Developing Dry Powder Inhaler Formulation
por: Sharif, Shahjabeen, et al.
Publicado: (2023)