Raptor determines β-cell identity and plasticity independent of hyperglycemia in mice

Compromised β-cell identity is emerging as an important contributor to β-cell failure in diabetes; however, the precise mechanism independent of hyperglycemia is under investigation. We have previously reported that mTORC1/Raptor regulates functional maturation in β-cells. In the present study, we f...

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Detalles Bibliográficos
Autores principales: Yin, Qinglei, Ni, Qicheng, Wang, Yichen, Zhang, Hongli, Li, Wenyi, Nie, Aifang, Wang, Shu, Gu, Yanyun, Wang, Qidi, Ning, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242325/
https://www.ncbi.nlm.nih.gov/pubmed/32439909
http://dx.doi.org/10.1038/s41467-020-15935-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242325/
https://www.ncbi.nlm.nih.gov/pubmed/32439909
http://dx.doi.org/10.1038/s41467-020-15935-0

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