LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma

Temozolomide (TMZ) resistance is a major cause of recurrence and poor prognosis in glioblastoma (GBM). Recently, increasing evidences suggested that long noncoding RNAs (LncRNAs) modulate GBM biological processes, especially in resistance to chemotherapy, but their role in TMZ chemoresistance has no...

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Detalles Bibliográficos
Autores principales: Liu, Boyang, Zhou, Jian, Wang, Chenyang, Chi, Yajie, Wei, Quantang, Fu, Zhao, Lian, Changlin, Huang, Qiongzhen, Liao, Chenxin, Yang, Zhao, Zeng, Huijun, Xu, Ningbo, Guo, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242335/
https://www.ncbi.nlm.nih.gov/pubmed/32439916
http://dx.doi.org/10.1038/s41419-020-2540-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242335/
https://www.ncbi.nlm.nih.gov/pubmed/32439916
http://dx.doi.org/10.1038/s41419-020-2540-y

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