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LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma
Temozolomide (TMZ) resistance is a major cause of recurrence and poor prognosis in glioblastoma (GBM). Recently, increasing evidences suggested that long noncoding RNAs (LncRNAs) modulate GBM biological processes, especially in resistance to chemotherapy, but their role in TMZ chemoresistance has no...
Autores principales: | Liu, Boyang, Zhou, Jian, Wang, Chenyang, Chi, Yajie, Wei, Quantang, Fu, Zhao, Lian, Changlin, Huang, Qiongzhen, Liao, Chenxin, Yang, Zhao, Zeng, Huijun, Xu, Ningbo, Guo, Hongbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242335/ https://www.ncbi.nlm.nih.gov/pubmed/32439916 http://dx.doi.org/10.1038/s41419-020-2540-y |
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