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GSEA-assisted gene signatures valid for combinations of prognostic markers in PCNSL

Primary central nervous system lymphoma (PCNSL) is a brain malignant non-Hodgkin’s B-cell lymphoma. The standard treatments are high-dose methotrexate (MTX)-based chemotherapies and deferred whole brain radiotherapy. However, MTX resistance-dependent global expression and signaling pathway changes a...

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Detalles Bibliográficos
Autores principales: Takashima, Yasuo, Hamano, Momoko, Fukai, Junya, Iwadate, Yasuo, Kajiwara, Koji, Kobayashi, Tsutomu, Hondoh, Hiroaki, Yamanaka, Ryuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242340/
https://www.ncbi.nlm.nih.gov/pubmed/32439996
http://dx.doi.org/10.1038/s41598-020-65463-6