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Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers

Tumor heterogeneity is common in cancer, however recent studies have applied single gene expression signatures to classify bladder cancers into distinct subtypes. Such stratification assumes that a predominant transcriptomic signature is sufficient to predict progression kinetics, patient survival a...

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Detalles Bibliográficos
Autores principales: Sfakianos, John P., Daza, Jorge, Hu, Yang, Anastos, Harry, Bryant, Geoffrey, Bareja, Rohan, Badani, Ketan K., Galsky, Matthew D., Elemento, Olivier, Faltas, Bishoy M., Mulholland, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242345/
https://www.ncbi.nlm.nih.gov/pubmed/32439865
http://dx.doi.org/10.1038/s41467-020-16162-3