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Constructing chiral bicyclo[3.2.1]octanes via palladium-catalyzed asymmetric tandem Heck/carbonylation desymmetrization of cyclopentenes

Transition-metal-catalyzed tandem Heck/carbonylation reaction has emerged as a powerful tool for the synthesis of structurally diverse carbonyl molecules, as well as natural products and pharmaceuticals. However, the asymmetric version was rarely reported, and remains a challenging topic. Herein, we...

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Detalles Bibliográficos
Autores principales: Yuan, Zhenbo, Zeng, Yuye, Feng, Ziwen, Guan, Zhe, Lin, Aijun, Yao, Hequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242361/
https://www.ncbi.nlm.nih.gov/pubmed/32439921
http://dx.doi.org/10.1038/s41467-020-16221-9