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β-arrestin2 deficiency protects against hepatic fibrosis in mice and prevents synthesis of extracellular matrix

Hepatic fibrosis is a disease of the wound-healing response following chronic liver injury, and activated hepatic stellate cells (HSCs) play a crucial role in the progression of hepatic fibrosis. β-arrestin2 functions as a multiprotein scaffold to coordinate complex signal transduction networks. Alt...

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Detalles Bibliográficos
Autores principales: Sun, Wu-Yi, Gu, Yuan-Jing, Li, Xin-Ran, Sun, Jia-Chang, Du, Jia-Jia, Chen, Jing-Yu, Ma, Yang, Wang, Qing-Tong, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242363/
https://www.ncbi.nlm.nih.gov/pubmed/32439968
http://dx.doi.org/10.1038/s41419-020-2596-8