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β-arrestin2 deficiency protects against hepatic fibrosis in mice and prevents synthesis of extracellular matrix
Hepatic fibrosis is a disease of the wound-healing response following chronic liver injury, and activated hepatic stellate cells (HSCs) play a crucial role in the progression of hepatic fibrosis. β-arrestin2 functions as a multiprotein scaffold to coordinate complex signal transduction networks. Alt...
Autores principales: | Sun, Wu-Yi, Gu, Yuan-Jing, Li, Xin-Ran, Sun, Jia-Chang, Du, Jia-Jia, Chen, Jing-Yu, Ma, Yang, Wang, Qing-Tong, Wei, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242363/ https://www.ncbi.nlm.nih.gov/pubmed/32439968 http://dx.doi.org/10.1038/s41419-020-2596-8 |
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