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Clinically relevant mutations in mycobacterial LepA cause rifampicin-specific phenotypic resistance
Although all wild-type bacterial populations exhibit antibiotic tolerance, bacterial mutants with higher or lower tolerant subpopulation sizes have been described. We recently showed that in mycobacteria, phenotypically-resistant subpopulations can grow in bulk-lethal concentrations of rifampicin, a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242378/ https://www.ncbi.nlm.nih.gov/pubmed/32439911 http://dx.doi.org/10.1038/s41598-020-65308-2 |