Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics

Mitochondria undergo dynamic fusion/fission, biogenesis and mitophagy in response to stimuli or stresses. Disruption of mitochondrial homeostasis could lead to cell senescence, although the underlying mechanism remains unclear. We show that deletion of mitochondrial phosphatase PGAM5 leads to accele...

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Detalles Bibliográficos
Autores principales: Yu, Bo, Ma, Jing, Li, Jing, Wang, Dazhi, Wang, Zhigao, Wang, Shusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242393/
https://www.ncbi.nlm.nih.gov/pubmed/32439975
http://dx.doi.org/10.1038/s41467-020-16312-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242393/
https://www.ncbi.nlm.nih.gov/pubmed/32439975
http://dx.doi.org/10.1038/s41467-020-16312-7

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