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Holliday junction recognition protein promotes pancreatic cancer growth and metastasis via modulation of the MDM2/p53 signaling

Holliday junction recognition protein (HJURP) refers to a histone H3 chaperone that has been implicated in different kinds of malignancies. Yet, its character in pancreatic cancer remains unclear. The expression of HJURP was assessed in PDAC tissues by RT-qPCR, immunoblotting, and immunohistochemist...

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Detalles Bibliográficos
Autores principales: Wang, Chen-jing, Li, Xin, Shi, Ping, Ding, Hai-yan, Liu, Yan-ping, Li, Ting, Lin, Ping-ping, Wang, Yun-shan, Zhang, Guo-qing, Cao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242411/
https://www.ncbi.nlm.nih.gov/pubmed/32439850
http://dx.doi.org/10.1038/s41419-020-2595-9