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Dual roles of the sterol recognition region in Hedgehog protein modification

Nature provides a number of mechanisms to encode dynamic information in biomolecules. In metazoans, there exist rare chemical modifications that occur in entirely unique regimes. One such example occurs in the Hedgehog (Hh) morphogens, proteins singular across all domains of life for the nature of t...

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Detalles Bibliográficos
Autores principales: Purohit, Rahul, Peng, Daniel S., Vielmas, Erika, Ondrus, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242414/
https://www.ncbi.nlm.nih.gov/pubmed/32440000
http://dx.doi.org/10.1038/s42003-020-0977-2