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Active metabolism unmasks functional protein–protein interactions in real time in-cell NMR
Protein–protein interactions, PPIs, underlie most cellular processes, but many PPIs depend on a particular metabolic state that can only be observed in live, actively metabolizing cells. Real time in-cell NMR spectroscopy, RT-NMR, utilizes a bioreactor to maintain cells in an active metabolic state....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242440/ https://www.ncbi.nlm.nih.gov/pubmed/32439966 http://dx.doi.org/10.1038/s42003-020-0976-3 |