High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression

Microtubule affinity regulating kinase 4 (MARK4) plays a crucial role in the regulation of NOD-like receptor pyrin domain 3 (NLRP3) inflammasome activation, which leads to the generation of bioactive interleukin (IL)-1β and IL-18. E74-like ETS transcription factor 3 (ELF3) participates in endothelia...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Shen, Xuefang, Liu, Jing, Chen, Wankun, Wu, Fengfeng, Wu, Weifei, Meng, Zhipeng, Zhu, Minmin, Miao, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242464/
https://www.ncbi.nlm.nih.gov/pubmed/32439949
http://dx.doi.org/10.1038/s41419-020-2598-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242464/
https://www.ncbi.nlm.nih.gov/pubmed/32439949
http://dx.doi.org/10.1038/s41419-020-2598-6

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