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CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts
Previous studies indicated that Ca(2+)/calmodulin-dependent kinase II (CaMKII), a kinase involved in the modulation of ryanodine receptor activity, activates Ca(2+)-regulated protease μ-calpain to promote myocardial ischemia/reperfusion injury. This study was performed to explore the underlying mech...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242471/ https://www.ncbi.nlm.nih.gov/pubmed/32439852 http://dx.doi.org/10.1038/s41419-020-2605-y |