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PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass
Bone turnover, which is determined by osteoclast-mediated bone resorption and osteoblast-mediated bone formation, represents a highly energy consuming process. The metabolic requirements of osteoblast differentiation and mineralization, both essential for regular bone formation, however, remain inco...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242479/ https://www.ncbi.nlm.nih.gov/pubmed/32439961 http://dx.doi.org/10.1038/s41598-020-65305-5 |