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PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass
Bone turnover, which is determined by osteoclast-mediated bone resorption and osteoblast-mediated bone formation, represents a highly energy consuming process. The metabolic requirements of osteoblast differentiation and mineralization, both essential for regular bone formation, however, remain inco...
Autores principales: | Müller, Dorothea I. H., Stoll, Cornelia, Palumbo-Zerr, Katrin, Böhm, Christina, Krishnacoumar, Brenda, Ipseiz, Natacha, Taubmann, Jule, Zimmermann, Max, Böttcher, Martin, Mougiakakos, Dimitrios, Tuckermann, Jan, Djouad, Farida, Schett, Georg, Scholtysek, Carina, Krönke, Gerhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242479/ https://www.ncbi.nlm.nih.gov/pubmed/32439961 http://dx.doi.org/10.1038/s41598-020-65305-5 |
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