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Mucosal Tuft Cell Density Is Increased in Diarrhea-Predominant Irritable Bowel Syndrome Colonic Biopsies

Tuft cells are rare chemosensory sentinels found in the gut epithelium. When triggered by helminth infection, tuft cells secrete interleukin-25 (IL-25) basolaterally and subsequently evoke an immune response. Irritable bowel syndrome (IBS) is a common and heterogeneous disorder characterized by bowe...

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Detalles Bibliográficos
Autores principales: Aigbologa, Jessica, Connolly, Maeve, Buckley, Julliette M., O'Malley, Dervla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242613/
https://www.ncbi.nlm.nih.gov/pubmed/32477197
http://dx.doi.org/10.3389/fpsyt.2020.00436