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The Use of Computational Approaches in the Discovery and Mechanism Study of Opioid Analgesics
Opioid receptors that belong to class A G protein-coupled receptors (GPCRs) are vital in pain control. In the past few years, published high-resolution crystal structures of opioid receptor laid a solid basis for both experimental and computational studies. Computer-aided drug design (CADD) has been...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242749/ https://www.ncbi.nlm.nih.gov/pubmed/32500054 http://dx.doi.org/10.3389/fchem.2020.00335 |