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MetaPhat: Detecting and Decomposing Multivariate Associations From Univariate Genome-Wide Association Statistics

BACKGROUND: Multivariate testing tools that integrate multiple genome-wide association studies (GWAS) have become important as the number of phenotypes gathered from study cohorts and biobanks has increased. While these tools have been shown to boost statistical power considerably over univariate te...

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Detalles Bibliográficos
Autores principales: Lin, Jake, Tabassum, Rubina, Ripatti, Samuli, Pirinen, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242752/
https://www.ncbi.nlm.nih.gov/pubmed/32499813
http://dx.doi.org/10.3389/fgene.2020.00431