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RPE Cells Engulf Microvesicles Secreted by Degenerating Rod Photoreceptors
Rhodopsin is mislocalized to the inner segment plasma membrane (IS PM) in various blinding disorders including autosomal-dominant retinitis pigmentosa caused by class I rhodopsin mutations. In these disorders, rhodopsin-laden microvesicles are secreted into the extracellular milieu by afflicted phot...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Society for Neuroscience
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242815/ https://www.ncbi.nlm.nih.gov/pubmed/32376599 http://dx.doi.org/10.1523/ENEURO.0507-19.2020 |