ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors

Natural genetic variants of Neuregulin1 (NRG1) and its cognate receptor ErbB4 are associated with a risk for schizophrenia. Whereas most studies on NRG1-ErbB4 signaling have focused on GABAergic interneurons, ErbB4 is also expressed by midbrain dopaminergic neurons where it modulates extracellular d...

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Detalles Bibliográficos
Autores principales: Skirzewski, Miguel, Cronin, Marie E., Murphy, Ricardo, Fobbs, Wambura, Kravitz, Alexxai V., Buonanno, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242816/
https://www.ncbi.nlm.nih.gov/pubmed/32354758
http://dx.doi.org/10.1523/ENEURO.0395-19.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242816/
https://www.ncbi.nlm.nih.gov/pubmed/32354758
http://dx.doi.org/10.1523/ENEURO.0395-19.2020

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