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ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors
Natural genetic variants of Neuregulin1 (NRG1) and its cognate receptor ErbB4 are associated with a risk for schizophrenia. Whereas most studies on NRG1-ErbB4 signaling have focused on GABAergic interneurons, ErbB4 is also expressed by midbrain dopaminergic neurons where it modulates extracellular d...
Autores principales: | Skirzewski, Miguel, Cronin, Marie E., Murphy, Ricardo, Fobbs, Wambura, Kravitz, Alexxai V., Buonanno, Andres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242816/ https://www.ncbi.nlm.nih.gov/pubmed/32354758 http://dx.doi.org/10.1523/ENEURO.0395-19.2020 |
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