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Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson’s Disease?

Parkinson’s disease (PD) is a slowly progressing neurodegenerative disorder that is coupled to both widespread protein aggregation and to loss of substantia nigra dopamine (DA) neurons, resulting in a wide variety of motor and non-motor signs and symptoms. Recent findings suggest that the PD process...

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Detalles Bibliográficos
Autores principales: von Linstow, Christian U., DeLano-Taylor, Merritt, Kordower, Jeffrey H., Brundin, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242832/
https://www.ncbi.nlm.nih.gov/pubmed/31958098
http://dx.doi.org/10.3233/JPD-191877