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Protein Quality Control Pathways at the Crossroad of Synucleinopathies

The pathophysiology of Parkinson’s disease, dementia with Lewy bodies, multiple system atrophy, and many others converge at alpha-synuclein (α-Syn) aggregation. Although it is still not entirely clear what precise biophysical processes act as triggers, cumulative evidence points towards a crucial ro...

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Detalles Bibliográficos
Autores principales: De Mattos, Eduardo P., Wentink, Anne, Nussbaum-Krammer, Carmen, Hansen, Christian, Bergink, Steven, Melki, Ronald, Kampinga, Harm H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242842/
https://www.ncbi.nlm.nih.gov/pubmed/31985474
http://dx.doi.org/10.3233/JPD-191790