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Metabolic insights from a GHSR-A203E mutant mouse model

OBJECTIVE: Binding of ghrelin to its receptor, growth hormone secretagogue receptor (GHSR), stimulates GH release, induces eating, and increases blood glucose. These processes may also be influenced by constitutive (ghrelin-independent) GHSR activity, as suggested by findings in short people with na...

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Detalles Bibliográficos
Autores principales: Torz, Lola J., Osborne-Lawrence, Sherri, Rodriguez, Juan, He, Zhenyan, Cornejo, María Paula, Mustafá, Emilio Román, Jin, Chunyu, Petersen, Natalia, Hedegaard, Morten A., Nybo, Maja, Damonte, Valentina Martínez, Metzger, Nathan P., Mani, Bharath K., Williams, Kevin W., Raingo, Jesica, Perello, Mario, Holst, Birgitte, Zigman, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242877/
https://www.ncbi.nlm.nih.gov/pubmed/32339772
http://dx.doi.org/10.1016/j.molmet.2020.101004