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Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 β-Xylosidases

The glycoside hydrolase family 39 (GH39) is a functionally expanding family with limited understanding about the molecular basis for substrate specificity and extremophilicity. In this work, we demonstrate the key role of the positive-subsite region in modulating substrate affinity and how the lack...

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Detalles Bibliográficos
Autores principales: de Morais, Mariana Abrahão Bueno, Polo, Carla Cristina, Domingues, Mariane Noronha, Persinoti, Gabriela Felix, Pirolla, Renan Augusto Siqueira, de Souza, Flávio Henrique Moreira, Correa, Jessica Batista de Lima, dos Santos, Camila Ramos, Murakami, Mário Tyago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242879/
https://www.ncbi.nlm.nih.gov/pubmed/32500063
http://dx.doi.org/10.3389/fbioe.2020.00419