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Exploring the Molecular Basis for Substrate Affinity and Structural Stability in Bacterial GH39 β-Xylosidases
The glycoside hydrolase family 39 (GH39) is a functionally expanding family with limited understanding about the molecular basis for substrate specificity and extremophilicity. In this work, we demonstrate the key role of the positive-subsite region in modulating substrate affinity and how the lack...
Autores principales: | de Morais, Mariana Abrahão Bueno, Polo, Carla Cristina, Domingues, Mariane Noronha, Persinoti, Gabriela Felix, Pirolla, Renan Augusto Siqueira, de Souza, Flávio Henrique Moreira, Correa, Jessica Batista de Lima, dos Santos, Camila Ramos, Murakami, Mário Tyago |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242879/ https://www.ncbi.nlm.nih.gov/pubmed/32500063 http://dx.doi.org/10.3389/fbioe.2020.00419 |
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