CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes

G protein-coupled receptors are a major class of membrane receptors that mediate physiological and pathophysiological cellular signaling. Many aspects of receptor activation and signaling can be investigated using genetically encoded luminescent fusion proteins. However, the use of these biosensors...

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Detalles Bibliográficos
Autores principales: White, Carl W., Caspar, Birgit, Vanyai, Hannah K., Pfleger, Kevin D.G., Hill, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242902/
https://www.ncbi.nlm.nih.gov/pubmed/32053779
http://dx.doi.org/10.1016/j.chembiol.2020.01.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242902/
https://www.ncbi.nlm.nih.gov/pubmed/32053779
http://dx.doi.org/10.1016/j.chembiol.2020.01.010

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