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Spleen tyrosine kinase inhibition is an effective treatment for established vasculitis in a pre-clinical model

The anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV) are a group of life-threatening multi-system diseases characterized by necrotising inflammation of small blood vessels and crescentic glomerulonephritis. ANCA are thought to play a direct pathogenic role. Previous studies ha...

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Detalles Bibliográficos
Autores principales: McAdoo, Stephen P., Prendecki, Maria, Tanna, Anisha, Bhatt, Tejal, Bhangal, Gurjeet, McDaid, John, Masuda, Esteban S., Cook, H. Terence, Tam, Frederick W.K., Pusey, Charles D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242903/
https://www.ncbi.nlm.nih.gov/pubmed/32305129
http://dx.doi.org/10.1016/j.kint.2019.12.014