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Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

Somatic stem cells expand massively during tissue regeneration, which might require control of cell fitness, allowing elimination of non-competitive, potentially harmful cells. How or if such cells are removed to restore organ function is not fully understood. Here, we show that a substantial fracti...

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Detalles Bibliográficos
Autores principales: Sreenivasan, Krishnamoorthy, Ianni, Alessandro, Künne, Carsten, Strilic, Boris, Günther, Stefan, Perdiguero, Eusebio, Krüger, Marcus, Spuler, Simone, Offermanns, Stefan, Gómez-del Arco, Pablo, Redondo, Juan Miguel, Munoz-Canoves, Pura, Kim, Johnny, Braun, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242912/
https://www.ncbi.nlm.nih.gov/pubmed/32433961
http://dx.doi.org/10.1016/j.celrep.2020.107652