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Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles
Somatic stem cells expand massively during tissue regeneration, which might require control of cell fitness, allowing elimination of non-competitive, potentially harmful cells. How or if such cells are removed to restore organ function is not fully understood. Here, we show that a substantial fracti...
Autores principales: | Sreenivasan, Krishnamoorthy, Ianni, Alessandro, Künne, Carsten, Strilic, Boris, Günther, Stefan, Perdiguero, Eusebio, Krüger, Marcus, Spuler, Simone, Offermanns, Stefan, Gómez-del Arco, Pablo, Redondo, Juan Miguel, Munoz-Canoves, Pura, Kim, Johnny, Braun, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242912/ https://www.ncbi.nlm.nih.gov/pubmed/32433961 http://dx.doi.org/10.1016/j.celrep.2020.107652 |
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