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Dexmedetomidine protects PC12 cells from ropivacaine injury through miR-381/LRRC4 /SDF-1/CXCR4 signaling pathway

INTRODUCTION: Ropivacaine has been regularly used because of its good anesthetic and analgesic effects, but it may exert neurotoxic effects on neurocyte. Dexmedetomidine has presented special advantages in the fields of neuroprotection, and it also could improve peripheral nerve block combining with...

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Detalles Bibliográficos
Autores principales: Xue, Ying, Xu, Tao, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243045/
https://www.ncbi.nlm.nih.gov/pubmed/32467829
http://dx.doi.org/10.1016/j.reth.2020.03.001