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Image-Based Marker-Free Screening of GABA(A) Agonists, Antagonists, and Modulators

The ionotropic GABA(A) receptors represent the main target for different groups of widely used drugs having hypnotic and anxiolytic effects. So far, most approaches used to assess GABA activity involve invasive low -throughput electrophysiological techniques or rely on fluorescent dyes, preventing t...

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Detalles Bibliográficos
Autores principales: Rappaz, Benjamin, Jourdain, Pascal, Banfi, Damiano, Kuttler, Fabien, Marquet, Pierre, Turcatti, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243081/
https://www.ncbi.nlm.nih.gov/pubmed/31779505
http://dx.doi.org/10.1177/2472555219887142