Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene decrease the structural stability and function of the CFTR protein, resulting in cystic fibrosis. Recently, the effect of CFTR-targeting combination therapy has dramatically increased, and it is expected that add-on dru...

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Detalles Bibliográficos
Autores principales: Fukuda, Ryosuke, Okiyoneda, Tsukasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243099/
https://www.ncbi.nlm.nih.gov/pubmed/32331485
http://dx.doi.org/10.3390/ph13040075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243099/
https://www.ncbi.nlm.nih.gov/pubmed/32331485
http://dx.doi.org/10.3390/ph13040075

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