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Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat

Hypertension plays an important role in the development and progression of chronic kidney disease. Studies to date, with mineralocorticoid receptor antagonists (MRA), have demonstrated varying degrees of results in modifying the development of renal fibrosis. This study aimed to investigate whether...

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Detalles Bibliográficos
Autores principales: Leader, Catherine J., Kelly, Darren J., Sammut, Ivan A., Wilkins, Gerard T., Walker, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243196/
https://www.ncbi.nlm.nih.gov/pubmed/32441493
http://dx.doi.org/10.14814/phy2.14448