Rescue of HSP70 in Spinal Neurons Alleviates Opioids-Induced Hyperalgesia via the Suppression of Endoplasmic Reticulum Stress in Rodents

A major unresolved issue in treating pain is the paradoxical hyperalgesia produced by the gold-standard analgesic morphine and other opioids. Endoplasmic reticulum (ER) stress has been shown to contribute to neuropathic or inflammatory pain, but its roles in opioids-induced hyperalgesia (OIH) are el...

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Detalles Bibliográficos
Autores principales: Lin, Tong-Tong, Qu, Jie, Wang, Chao-Yu, Yang, Xing, Hu, Fan, Hu, Liang, Wu, Xue-Feng, Jiang, Chun-Yi, Liu, Wen-Tao, Han, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243285/
https://www.ncbi.nlm.nih.gov/pubmed/32500072
http://dx.doi.org/10.3389/fcell.2020.00269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243285/
https://www.ncbi.nlm.nih.gov/pubmed/32500072
http://dx.doi.org/10.3389/fcell.2020.00269

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